Cargando…

miR‐322‐5p targets IGF‐1 and is suppressed in the heart of rats with pulmonary hypertension

Pulmonary arterial hypertension (PAH) is characterised by remodelling of the pulmonary vasculature leading to right ventricular hypertrophy. Here, we show that miR‐322‐5p (the rodent orthologue of miR‐424‐5p) expression is decreased in the right ventricle of monocrotaline‐treated rats, a model of PA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Connolly, Martin, Garfield, Benjamin E., Crosby, Alexi, Morrell, Nick W., Wort, Stephen J., Kemp, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832985/ https://www.ncbi.nlm.nih.gov/pubmed/29511611 http://dx.doi.org/10.1002/2211-5463.12369

Ejemplares similares

miR-1-5p targets TGF-βR1 and is suppressed in the hypertrophying hearts of rats with pulmonary arterial hypertension
por: Connolly, Martin, et al.
Publicado: (2020)

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension
por: Garfield, Benjamin E, et al.
Publicado: (2019)

Mouse oocytes suppress miR-322-5p expression in ovarian granulosa cells
por: SUMITOMO, Jun-ichi, et al.
Publicado: (2016)

miR-424(322)-5p targets Ezh1 to inhibit the proliferation and differentiation of myoblasts : miR-424(322)-5p regulates the proliferation and differentiation of myoblasts
por: Yue, Yongqi, et al.
Publicado: (2023)

MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation
por: Zhao, Meng-Jie, et al.
Publicado: (2019)

H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors
por: Liang, Rui, et al.
Publicado: (2021)

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
por: Llobet-Navas, David, et al.
Publicado: (2014)

TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis
por: Li, Meng, et al.
Publicado: (2022)

Downregulation of miR-322 promotes apoptosis of GC-2 cell by targeting Ddx3x
por: Che, Qi, et al.
Publicado: (2019)

Fetal malnutrition-induced catch up failure is caused by elevated levels of miR-322 in rats
por: Nemoto, Takahiro, et al.
Publicado: (2020)

Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension
por: Long, Lu, et al.
Publicado: (2020)

MicroRNA 322 Aggravates Dexamethasone-Induced Muscle Atrophy by Targeting IGF1R and INSR
por: Geng, Hongwei, et al.
Publicado: (2020)

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells
por: Zeng, Yan, et al.
Publicado: (2015)

MiR-223 Suppresses Cell Proliferation by Targeting IGF-1R
por: Jia, Cheng You, et al.
Publicado: (2011)

MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer
por: Su, Jiaojiao, et al.
Publicado: (2014)

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling
por: Hurst, Liam A., et al.
Publicado: (2017)

322. Joint Spacer Retention, Antimicrobial Suppression, and Risk of Re-infection
por: Valencia, Jose Carlo, et al.
Publicado: (2018)

H19X-encoded miR-424(322)/-503 cluster: emerging roles in cell differentiation, proliferation, plasticity and metabolism
por: Wang, Fan, et al.
Publicado: (2018)

miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy
por: Rodriguez-Barrueco, Ruth, et al.
Publicado: (2017)

Reviewers BJCVS 32.2
Publicado: (2017)

Tumoral pulmonary hypertension
por: Price, Laura C., et al.
Publicado: (2019)

MiR-143 Targets IGF-1R to Suppress Autoimmunity in Thyroid-Associated Ophthalmopathy
por: Tang, Wei, et al.
Publicado: (2022)

miR-322/-503 rescues myoblast defects in myotonic dystrophy type 1 cell model by targeting CUG repeats
por: Shen, Xiaopeng, et al.
Publicado: (2020)

miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4
por: Liu, Yu‐si, et al.
Publicado: (2020)

MiR-322-5p Alleviates Cell Injury and Impairment of Cognitive Function in Vascular Dementia by Targeting TSPAN5
por: Zheng, Wei, et al.
Publicado: (2022)

Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin
por: Wang, Ran, et al.
Publicado: (2018)

Corin Missense Variants, Blood Pressure, and Hypertension in 11 322 Black Individuals: Insights From REGARDS and the Jackson Heart Study
por: Parcha, Vibhu, et al.
Publicado: (2022)

Pulmonary vasodilator treatment in pulmonary hypertension due to left heart or lung disease: time for a high-definition picture?
por: Piccari, Lucilla, et al.
Publicado: (2021)

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice
por: Crosby, Alexi, et al.
Publicado: (2018)

MiR-505 suppressed the growth of hepatocellular carcinoma cells via targeting IGF-1R
por: Ren, Liang, et al.
Publicado: (2019)

Inhibition of Smurf2 translation by miR-322/503 modulates TGF-β/Smad2 signaling and intestinal epithelial homeostasis
por: Cao, Shan, et al.
Publicado: (2014)

miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint
por: Xu, Shaohua, et al.
Publicado: (2016)

Serum miR-204 and miR-451 Expression and Diagnostic Value in Patients with Pulmonary Artery Hypertension Triggered by Congenital Heart Disease
por: Ji, Dejiang, et al.
Publicado: (2022)

p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure
por: Huang, Chih-Yang, et al.
Publicado: (2017)

Congenital second-degree heart block and total anomalous pulmonary venous return associated with microduplication of 1q32.2
por: Puvabanditsin, Surasak, et al.
Publicado: (2018)

Progress in the understanding and management of pulmonary arterial hypertension
por: Chakrabarti, A.M., et al.
Publicado: (2015)

IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer
por: Cui, Hengmi, et al.
Publicado: (2016)

Retracted: Serum miR-204 and miR-451 Expression and Diagnostic Value in Patients with Pulmonary Artery Hypertension Triggered by Congenital Heart Disease
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

miR‐424‐5p reduces ribosomal RNA and protein synthesis in muscle wasting
por: Connolly, Martin, et al.
Publicado: (2017)

32.2 ABNORMALITIES OF SYNAPTIC PROTEOMES IN SCHIZOPHRENIA
por: Funk, Adam, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ihaplim6isd345pit4qp4312se