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Osteoglycin (OGN) reverses epithelial to mesenchymal transition and invasiveness in colorectal cancer via EGFR/Akt pathway

BACKGROUND: Many types of cancers are devoid of the small leucine-rich proteoglycans: osteoglycin (OGN), but its role in tumorigenesis is poorly studied especially in colorectal cancers (CRC). Here we aim to evaluate the relationship between OGN expression patterns and the clinical course of CRC, an...

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Detalles Bibliográficos
Autores principales: Hu, Xiang, Li, Ya-Qi, Li, Qing-Guo, Ma, Yan-Lei, Peng, Jun-Jie, Cai, San-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833032/
https://www.ncbi.nlm.nih.gov/pubmed/29499765
http://dx.doi.org/10.1186/s13046-018-0718-2