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Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

BACKGROUND: Preeclampsia (PE) is a heterogeneous, hypertensive disorder of pregnancy, with no robust biomarkers or effective treatments. We hypothesized that this heterogeneity is due to the existence of multiple subtypes of PE and, in support of this hypothesis, we recently identified five clusters...

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Detalles Bibliográficos
Autores principales: Leavey, Katherine, Wilson, Samantha L., Bainbridge, Shannon A., Robinson, Wendy P., Cox, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833042/
https://www.ncbi.nlm.nih.gov/pubmed/29507646
http://dx.doi.org/10.1186/s13148-018-0463-6