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RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects the motor neuromuscular system leading to complete paralysis and premature death. The multifactorial nature of ALS that involves both cell-autonomous and non-cell-autonomous processes contributes...

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Detalles Bibliográficos
Autores principales: Vallarola, Antonio, Sironi, Francesca, Tortarolo, Massimo, Gatto, Noemi, De Gioia, Roberta, Pasetto, Laura, De Paola, Massimiliano, Mariani, Alessandro, Ghosh, Supurna, Watson, Richard, Kalmes, Andreas, Bonetto, Valentina, Bendotti, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833072/
https://www.ncbi.nlm.nih.gov/pubmed/29495962
http://dx.doi.org/10.1186/s12974-018-1101-0