SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells

BACKGROUND: Abdominal aortic aneurysm (AAA) is a deadly cardiovascular disease characterised by the gradual, irreversible dilation of the abdominal aorta. AAA is a complex genetic disease but little is known about the role of epigenetics. Our objective was to determine if global DNA methylation and...

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Detalles Bibliográficos
Autores principales: Toghill, Bradley J., Saratzis, Athanasios, Freeman, Peter J., Sylvius, Nicolas, Bown, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833080/
https://www.ncbi.nlm.nih.gov/pubmed/29507647
http://dx.doi.org/10.1186/s13148-018-0460-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833080/
https://www.ncbi.nlm.nih.gov/pubmed/29507647
http://dx.doi.org/10.1186/s13148-018-0460-9

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