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SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells
BACKGROUND: Abdominal aortic aneurysm (AAA) is a deadly cardiovascular disease characterised by the gradual, irreversible dilation of the abdominal aorta. AAA is a complex genetic disease but little is known about the role of epigenetics. Our objective was to determine if global DNA methylation and...
Autores principales: | Toghill, Bradley J., Saratzis, Athanasios, Freeman, Peter J., Sylvius, Nicolas, Bown, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833080/ https://www.ncbi.nlm.nih.gov/pubmed/29507647 http://dx.doi.org/10.1186/s13148-018-0460-9 |
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