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Improving eukaryotic genome annotation using single molecule mRNA sequencing

BACKGROUND: The advantages of Pacific Biosciences (PacBio) single-molecule real-time (SMRT) technology include long reads, low systematic bias, and high consensus read accuracy. Here we use these attributes to improve on the genome annotation of the parasitic hookworm Ancylostoma ceylanicum using Pa...

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Detalles Bibliográficos
Autores principales: Magrini, Vincent, Gao, Xin, Rosa, Bruce A., McGrath, Sean, Zhang, Xu, Hallsworth-Pepin, Kymberlie, Martin, John, Hawdon, John, Wilson, Richard K., Mitreva, Makedonka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833154/
https://www.ncbi.nlm.nih.gov/pubmed/29495964
http://dx.doi.org/10.1186/s12864-018-4555-7