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In silico analysis of antibiotic-induced Clostridium difficile infection: Remediation techniques and biological adaptations
In this paper we study antibiotic-induced C. difficile infection (CDI), caused by the toxin-producing C. difficile (CD), and implement clinically-inspired simulated treatments in a computational framework that synthesizes a generalized Lotka-Volterra (gLV) model with SIR modeling techniques. The gLV...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833281/ https://www.ncbi.nlm.nih.gov/pubmed/29451873 http://dx.doi.org/10.1371/journal.pcbi.1006001 |