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Trade-off between synergy and efficacy in combinations of HIV-1 latency-reversing agents
Eradicating HIV-1 infection is difficult because of the reservoir of latently infected cells that gets established soon after infection, remains hidden from antiretroviral drugs and host immune responses, and retains the capacity to reignite infection following the cessation of treatment. Drugs call...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833289/ https://www.ncbi.nlm.nih.gov/pubmed/29451894 http://dx.doi.org/10.1371/journal.pcbi.1006004 |