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MCL-1 is a prognostic indicator and drug target in breast cancer

Analysis of publicly available genomic and gene expression data demonstrates that MCL1 expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl-2 family members, the short half-life of MCL-1 protein led us to investigate MCL-1 protein expression in a breast cancer tis...

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Detalles Bibliográficos
Autores principales: Campbell, Kirsteen J., Dhayade, Sandeep, Ferrari, Nicola, Sims, Andrew H., Johnson, Emma, Mason, Susan M., Dickson, Ashley, Ryan, Kevin M., Kalna, Gabriela, Edwards, Joanne, Tait, Stephen W. G., Blyth, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833338/
https://www.ncbi.nlm.nih.gov/pubmed/29339815
http://dx.doi.org/10.1038/s41419-017-0035-2