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FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathway

Epigenetic modifiers have emerged as critical factors governing the biology of different cancers. Herein we show that FBXL10 (also called KDM2B or JHDM1B), an important member of Polycomb repressive complexes, is overexpressed in human diffuse large B-cell lymphoma (DLBCL) tissues and the derived ce...

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Detalles Bibliográficos
Autores principales: Zhao, Xiujuan, Wang, Xing, Li, Qian, Chen, Wanbiao, Zhang, Na, Kong, Yu, Lv, Junqiang, Cao, Lei, Lin, Dan, Wang, Xi, Xu, Guogang, Wu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833345/
https://www.ncbi.nlm.nih.gov/pubmed/29352142
http://dx.doi.org/10.1038/s41419-017-0066-8