Mixed lineage kinase ZAK promotes epithelial–mesenchymal transition in cancer progression

ZAK, a mixed lineage kinase, is often described as a positive or negative regulator of cell growth. We identified it as one of the top hits in our kinome cDNA screen for potent regulators of epithelial mesenchymal transition (EMT). Ectopic expression of ZAK promoted EMT phenotypes and apoptosis resi...

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Detalles Bibliográficos
Autores principales: Li, Linna, Su, Ning, Zhou, Ting, Zheng, Dayong, Wang, Zheng, Chen, Haoyu, Yuan, Shoujun, Li, Wenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833348/
https://www.ncbi.nlm.nih.gov/pubmed/29396440
http://dx.doi.org/10.1038/s41419-017-0161-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833348/
https://www.ncbi.nlm.nih.gov/pubmed/29396440
http://dx.doi.org/10.1038/s41419-017-0161-x

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