Dual roles of miR-374a by modulated c-Jun respectively targets CCND1-inducing PI3K/AKT signal and PTEN-suppressing Wnt/β-catenin signaling in non-small-cell lung cancer

MiR-374a appears to play a complex role in non-small-cell lung cancer (NSCLC). Here, we demonstrate a dual role for miR-374a in NSCLC pathogenesis. The effects and modulatory mechanisms of miR-374a on cell growth, migration, invasion, and in vivo tumorigenesis and metastasis in nude mice were also a...

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Detalles Bibliográficos
Autores principales: Zhao, Mengyang, Xu, Ping, Liu, Zhen, Zhen, Yan, Chen, Yiyu, Liu, Yiyi, Fu, Qiaofen, Deng, Xiaojie, Liang, Zixi, Li, Yonghao, Lin, Xian, Fang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833350/
https://www.ncbi.nlm.nih.gov/pubmed/29362431
http://dx.doi.org/10.1038/s41419-017-0103-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833350/
https://www.ncbi.nlm.nih.gov/pubmed/29362431
http://dx.doi.org/10.1038/s41419-017-0103-7

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