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miR-143-3p targeting of ITGA6 suppresses tumour growth and angiogenesis by downregulating PLGF expression via the PI3K/AKT pathway in gallbladder carcinoma

Gallbladder cancer (GBC) is the most common malignant tumour of the biliary track system. Angiogenesis plays a pivotal role in the development and progression of malignant tumours. miR-143-3p acts as a tumour suppressor in various cancers. Their role in GBC is however less well defined. Here we show...

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Detalles Bibliográficos
Autores principales: Jin, Yun-Peng, Hu, Yun-Ping, Wu, Xiang-Song, Wu, Yao-Shi, Ye, Yuan-Yuan, Li, Huai-Feng, Liu, Yong-Chen, Jiang, Lin, Liu, Fa-Tao, Zhang, Yi-Jian, Hao, Ya-Juan, Liu, Xi-Yong, Liu, Ying-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833358/
https://www.ncbi.nlm.nih.gov/pubmed/29416013
http://dx.doi.org/10.1038/s41419-017-0258-2