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IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways

Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used in the clinic for bone defect reconstruction because of its powerful osteoinductive capacity. However, commercially available rhBMP-2 requires a high concentration in the clinical setting for consistent bone formation. A high do...

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Detalles Bibliográficos
Autores principales: Huang, Ru-Lin, Sun, Yangbai, Ho, Chia-Kang, Liu, Kai, Tang, Qi-Qun, Xie, Yun, Li, Qingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833364/
https://www.ncbi.nlm.nih.gov/pubmed/29396550
http://dx.doi.org/10.1038/s41419-017-0126-0