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IL-6 potentiates BMP-2-induced osteogenesis and adipogenesis via two different BMPR1A-mediated pathways
Recombinant human bone morphogenetic protein-2 (rhBMP-2) is widely used in the clinic for bone defect reconstruction because of its powerful osteoinductive capacity. However, commercially available rhBMP-2 requires a high concentration in the clinical setting for consistent bone formation. A high do...
Autores principales: | Huang, Ru-Lin, Sun, Yangbai, Ho, Chia-Kang, Liu, Kai, Tang, Qi-Qun, Xie, Yun, Li, Qingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833364/ https://www.ncbi.nlm.nih.gov/pubmed/29396550 http://dx.doi.org/10.1038/s41419-017-0126-0 |
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