Impairment of Fas-ligand–caveolin-1 interaction inhibits Fas-ligand translocation to rafts and Fas-ligand-induced cell death

Fas-ligand/CD178 belongs to the TNF family proteins and can induce apoptosis through death receptor Fas/CD95. The important requirement for Fas-ligand-dependent cell death induction is its localization to rafts, cholesterol- and sphingolipid-enriched micro-domains of membrane, involved in regulation...

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Detalles Bibliográficos
Autores principales: Glukhova, Xenia A., Trizna, Julia A., Proussakova, Olga V., Gogvadze, Vladimir, Beletsky, Igor P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833370/
https://www.ncbi.nlm.nih.gov/pubmed/29358576
http://dx.doi.org/10.1038/s41419-017-0109-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833370/
https://www.ncbi.nlm.nih.gov/pubmed/29358576
http://dx.doi.org/10.1038/s41419-017-0109-1

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