ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells

Cancer-initiating cells (CICs) are responsible for tumor initiation, progression, and therapeutic resistance; moreover, redox homeostasis is important in regulating cancer stemness. Previously, we have identified that cancer cells containing low intracellular reactive oxygen species levels (ROS(Low)...

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Detalles Bibliográficos
Autores principales: Chang, Ching-Wen, Chen, Yu-Syuan, Tsay, Yeou-Guang, Han, Chia-Li, Chen, Yu-Ju, Yang, Cheng-Chieh, Hung, Kai-Feng, Lin, Chao-Hsiung, Huang, Tsung-Yen, Kao, Shou-Yen, Lee, Te-Chang, Lo, Jeng-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833380/
https://www.ncbi.nlm.nih.gov/pubmed/29416012
http://dx.doi.org/10.1038/s41419-017-0250-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833380/
https://www.ncbi.nlm.nih.gov/pubmed/29416012
http://dx.doi.org/10.1038/s41419-017-0250-x

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