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AMP-activated protein kinase agonist N(6)-(3-hydroxyphenyl)adenosine protects against fulminant hepatitis by suppressing inflammation and apoptosis

Both AMP-activated protein kinase (AMPK) agonist and inhibitor have been reported to protect against fulminant hepatitis, implying that AMPK may play a complicated role in the development of fulminant hepatitis. In this study, we exploited whether the novel AMPK agonist N(6)-(3-hydroxyphenyl)adenosi...

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Detalles Bibliográficos
Autores principales: Li, Jin, Chen, Bo, Zhong, Liping, Gao, Feng, Zhu, Haibo, Wang, Fengzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833387/
https://www.ncbi.nlm.nih.gov/pubmed/29348606
http://dx.doi.org/10.1038/s41419-017-0118-0