Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling

BMP2 expression is spatiotemporally correlated with embryo implantation and is crucial for endometrial decidualization and fertility in mice. BMP2 has been reported to increase the mesenchymal adhesion molecule N-cadherin and enhance cell invasion in cancer cells; moreover, studies suggest that N-ca...

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Detalles Bibliográficos
Autores principales: Zhao, Hong-Jin, Klausen, Christian, Li, Yan, Zhu, Hua, Wang, Yan-Ling, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833391/
https://www.ncbi.nlm.nih.gov/pubmed/29416020
http://dx.doi.org/10.1038/s41419-017-0230-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833391/
https://www.ncbi.nlm.nih.gov/pubmed/29416020
http://dx.doi.org/10.1038/s41419-017-0230-1

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