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Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis

Cancer side-population (SP) represents a sub-population of stem-like cancer cells that have an important role in drug resistance due to their high expression of the ATP-binding cassette transporter ABCG2 involved in drug export. Auranofin (AF), a clinical drug of gold complex that is used in treatme...

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Detalles Bibliográficos
Autores principales: Hou, Guo-Xin, Liu, Pan-Pan, Zhang, Shengyi, Yang, Mengqi, Liao, Jianwei, Yang, Jing, Hu, Yumin, Jiang, Wen-Qi, Wen, Shijun, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833411/
https://www.ncbi.nlm.nih.gov/pubmed/29367724
http://dx.doi.org/10.1038/s41419-017-0159-4