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Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis
Cancer side-population (SP) represents a sub-population of stem-like cancer cells that have an important role in drug resistance due to their high expression of the ATP-binding cassette transporter ABCG2 involved in drug export. Auranofin (AF), a clinical drug of gold complex that is used in treatme...
Autores principales: | Hou, Guo-Xin, Liu, Pan-Pan, Zhang, Shengyi, Yang, Mengqi, Liao, Jianwei, Yang, Jing, Hu, Yumin, Jiang, Wen-Qi, Wen, Shijun, Huang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833411/ https://www.ncbi.nlm.nih.gov/pubmed/29367724 http://dx.doi.org/10.1038/s41419-017-0159-4 |
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