Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells

Senescence of cancer cells is an important outcome of treatment of many cancer types. Cell senescence is a permanent cell cycle arrest induced by stress conditions, including DNA damage. DNA damage activates DNA damage response (DDR), which involves members of the phosphatidylinositol 3-kinase-relat...

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Detalles Bibliográficos
Autores principales: Strzeszewska, Anna, Alster, Olga, Mosieniak, Grażyna, Ciolko, Agata, Sikora, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833415/
https://www.ncbi.nlm.nih.gov/pubmed/29352261
http://dx.doi.org/10.1038/s41419-017-0069-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833415/
https://www.ncbi.nlm.nih.gov/pubmed/29352261
http://dx.doi.org/10.1038/s41419-017-0069-5

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