Cargando…

Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells

Senescence of cancer cells is an important outcome of treatment of many cancer types. Cell senescence is a permanent cell cycle arrest induced by stress conditions, including DNA damage. DNA damage activates DNA damage response (DDR), which involves members of the phosphatidylinositol 3-kinase-relat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Strzeszewska, Anna, Alster, Olga, Mosieniak, Grażyna, Ciolko, Agata, Sikora, Ewa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833415/ https://www.ncbi.nlm.nih.gov/pubmed/29352261 http://dx.doi.org/10.1038/s41419-017-0069-5

Ejemplares similares

Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence()
por: Mosieniak, Grazyna, et al.
Publicado: (2015)

A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta
por: Bielak-Zmijewska, Anna, et al.
Publicado: (2013)

Therapy-Induced Senescent/Polyploid Cancer Cells Undergo Atypical Divisions Associated with Altered Expression of Meiosis, Spermatogenesis and EMT Genes
por: Czarnecka-Herok, Joanna, et al.
Publicado: (2022)

Cellular Senescence in Brain Aging
por: Sikora, Ewa, et al.
Publicado: (2021)

Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells
por: Piszczatowska, Katarzyna, et al.
Publicado: (2020)

The Role of Curcumin in the Modulation of Ageing
por: Bielak-Zmijewska, Anna, et al.
Publicado: (2019)

The Role of Nibrin in Doxorubicin-Induced Apoptosis and Cell Senescence in Nijmegen Breakage Syndrome Patients Lymphocytes
por: Alster, Olga, et al.
Publicado: (2014)

NOX4 downregulation leads to senescence of human vascular smooth muscle cells
por: Przybylska, Dorota, et al.
Publicado: (2016)

Curcumin induces multiple signaling pathways leading to vascular smooth muscle cell senescence
por: Grabowska, Wioleta, et al.
Publicado: (2019)

NF90 coordinately represses the senescence-associated secretory phenotype
por: Tominaga-Yamanaka, Kumiko, et al.
Publicado: (2012)

Curcumin induces senescence of primary human cells building the vasculature in a DNA damage and ATM-independent manner
por: Grabowska, Wioleta, et al.
Publicado: (2015)

Cell senescence, the senescence-associated secretory phenotype, and cancers
por: Langhi Prata, Larissa G. P., et al.
Publicado: (2023)

Unbiased proteomic analysis of extracellular vesicles secreted by senescent human vascular smooth muscle cells reveals their ability to modulate immune cell functions
por: Głuchowska, Agata, et al.
Publicado: (2022)

Chromatin-Directed Proteomics Identifies ZNF84 as a p53-Independent Regulator of p21 in Genotoxic Stress Response
por: Strzeszewska-Potyrała, Anna, et al.
Publicado: (2021)

Cellular senescence, senescence-associated secretory phenotype, and chronic kidney disease
por: Wang, Wen-Juan, et al.
Publicado: (2017)

Fiji-Based Tool for Rapid and Unbiased Analysis of SA-β-Gal Activity in Cultured Cells
por: Krzystyniak, Adam, et al.
Publicado: (2023)

Trabectedin modulates the senescence-associated secretory phenotype and promotes cell death in senescent tumor cells by targeting NF-κB
por: Camorani, Simona, et al.
Publicado: (2018)

Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype
por: Kumari, Ruchi, et al.
Publicado: (2021)

Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
por: Guan, Yiting, et al.
Publicado: (2020)

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice
por: Shrestha, Niraj, et al.
Publicado: (2023)

In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers
por: Samakkarnthai, Parinya, et al.
Publicado: (2023)

Is senescence-associated β-galactosidase a marker of neuronal senescence?
por: Piechota, Malgorzata, et al.
Publicado: (2016)

Diversity of the Senescence Phenotype of Cancer Cells Treated with Chemotherapeutic Agents
por: Bojko, Agnieszka, et al.
Publicado: (2019)

A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence
por: Meyer, Patrick, et al.
Publicado: (2017)

IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
por: Homann, Lorenzo, et al.
Publicado: (2022)

Ceria Nanoparticles Alleviated Osteoarthritis through Attenuating Senescence and Senescence-Associated Secretory Phenotype in Synoviocytes
por: Ren, Xunshan, et al.
Publicado: (2023)

Colchicine Protects against Ethanol-Induced Senescence and Senescence-Associated Secretory Phenotype in Endothelial Cells
por: Zhou, Huakang, et al.
Publicado: (2023)

Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype
por: Terlecki-Zaniewicz, Lucia, et al.
Publicado: (2018)

Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 Cells
por: Nagineni, Chandrasekharam N., et al.
Publicado: (2021)

MLL1 is essential for the senescence-associated secretory phenotype
por: Capell, Brian C., et al.
Publicado: (2016)

The Role of Senescence-Associated Secretory Phenotype in Bone Loss
por: Zhu, Runjiu, et al.
Publicado: (2022)

The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation
por: Huna, Anda, et al.
Publicado: (2023)

Emerging common themes in regulation of PIKKs and PI3Ks
por: Lempiäinen, Harri, et al.
Publicado: (2009)

From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
por: Byun, Hae-Ok, et al.
Publicado: (2015)

Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
por: Watanabe, Sugiko, et al.
Publicado: (2017)

Cellular senescence and senescence‐associated secretory phenotype via the cGAS‐STING signaling pathway in cancer
por: Loo, Tze Mun, et al.
Publicado: (2019)

The impact of cellular senescence and senescence‑associated secretory phenotype in cancer‑associated fibroblasts on the malignancy of pancreatic cancer
por: Higashiguchi, Masaya, et al.
Publicado: (2023)

Senescence‐associated tissue microenvironment promotes colon cancer formation through the secretory factor GDF15
por: Guo, Yuna, et al.
Publicado: (2019)

Endothelial progeria induces adipose tissue senescence and impairs insulin sensitivity through senescence associated secretory phenotype
por: Barinda, Agian Jeffilano, et al.
Publicado: (2020)

Impacts of Telomeric Length, Chronic Hypoxia, Senescence, and Senescence-Associated Secretory Phenotype on the Development of Thoracic Aortic Aneurysm
por: Aschacher, Thomas, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_h71lk2nscod1ad2225mvjl0233