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Insight into the role of PIKK family members and NF-кB in DNAdamage-induced senescence and senescence-associated secretory phenotype of colon cancer cells
Senescence of cancer cells is an important outcome of treatment of many cancer types. Cell senescence is a permanent cell cycle arrest induced by stress conditions, including DNA damage. DNA damage activates DNA damage response (DDR), which involves members of the phosphatidylinositol 3-kinase-relat...
Autores principales: | Strzeszewska, Anna, Alster, Olga, Mosieniak, Grażyna, Ciolko, Agata, Sikora, Ewa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833415/ https://www.ncbi.nlm.nih.gov/pubmed/29352261 http://dx.doi.org/10.1038/s41419-017-0069-5 |
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