DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice

Retinitis pigmentosa (RP) is a group of inherited retinal degenerative diseases causing progressive loss of photoreceptors. Numerous gene mutations are identified to be related with RP, but epigenetic modifications may also be involved in the pathogenesis. Previous studies suggested that both DNA me...

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Detalles Bibliográficos
Autores principales: Zheng, Shijie, Xiao, Lirong, Liu, Yu, Wang, Yujiao, Cheng, Lin, Zhang, Junjun, Yan, Naihong, Chen, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833420/
https://www.ncbi.nlm.nih.gov/pubmed/29472543
http://dx.doi.org/10.1038/s41419-018-0349-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833420/
https://www.ncbi.nlm.nih.gov/pubmed/29472543
http://dx.doi.org/10.1038/s41419-018-0349-8

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