PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis

Emerging evidence has shown that the PIM serine/threonine kinase family, including PIM1, PIM2 and PIM3, is associated with tumour progression towards metastasis. PIM1, an attractive molecular target, has been identified as a potential prognostic biomarker for haematological and epithelial malignanci...

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Detalles Bibliográficos
Autores principales: Zhao, Bin, Liu, Lei, Mao, Jun, Zhang, Zhiwei, Wang, Qifei, Li, Quanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833424/
https://www.ncbi.nlm.nih.gov/pubmed/29472550
http://dx.doi.org/10.1038/s41419-018-0348-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833424/
https://www.ncbi.nlm.nih.gov/pubmed/29472550
http://dx.doi.org/10.1038/s41419-018-0348-9

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