MicroRNA miR-4779 suppresses tumor growth by inducing apoptosis and cell cycle arrest through direct targeting of PAK2 and CCND3

Depending on the function of their target genes, microRNAs (miRNAs) act as either tumor suppressors or oncogenes. Therefore, miRNAs represent a novel therapeutic strategy for prevention and management of cancer by targeting of onco-miRNAs or mimicking of tumor suppressor miRNAs. Herein, we identifie...

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Detalles Bibliográficos
Autores principales: Koo, Kyung Hee, Kwon, Heechung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833427/
https://www.ncbi.nlm.nih.gov/pubmed/29362401
http://dx.doi.org/10.1038/s41419-017-0100-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833427/
https://www.ncbi.nlm.nih.gov/pubmed/29362401
http://dx.doi.org/10.1038/s41419-017-0100-x

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