MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

Upregulation of MYC and miRNAs deregulation are common in prostate cancer (PCa). Overactive MYC may cause miRNAs’ expression deregulation through transcriptional and post-transcriptional mechanisms and epigenetic alterations are also involved in miRNAs dysregulation. Herein, we aimed to elucidate th...

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Detalles Bibliográficos
Autores principales: Barros-Silva, Daniela, Costa-Pinheiro, Pedro, Duarte, Henrique, Sousa, Elsa Joana, Evangelista, Adriane Feijó, Graça, Inês, Carneiro, Isa, Martins, Ana Teresa, Oliveira, Jorge, Carvalho, André L., Marques, Márcia M., Henrique, Rui, Jerónimo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833437/
https://www.ncbi.nlm.nih.gov/pubmed/29415999
http://dx.doi.org/10.1038/s41419-017-0241-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833437/
https://www.ncbi.nlm.nih.gov/pubmed/29415999
http://dx.doi.org/10.1038/s41419-017-0241-y

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