Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling

Baicalin is a natural flavonoid glycoside which has potent anti-tumor and antioxidant activity in cancer cells. In the present study, we found that baicalin treatment significantly induced senescence in colon cancer cells. Furthermore, baicalin upregulated the expression of decidual protein induced...

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Detalles Bibliográficos
Autores principales: Wang, Zhou, Ma, Lingman, Su, Mengqi, Zhou, Yiran, Mao, Ke, Li, Chengqin, Peng, Guangyong, Zhou, Changlin, Shen, Baiyong, Dou, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833439/
https://www.ncbi.nlm.nih.gov/pubmed/29440765
http://dx.doi.org/10.1038/s41419-017-0223-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833439/
https://www.ncbi.nlm.nih.gov/pubmed/29440765
http://dx.doi.org/10.1038/s41419-017-0223-0

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