Antitumor activity of EGFR-specific CAR T cells against non-small-cell lung cancer cells in vitro and in mice

Effective control of non-small-cell lung cancer (NSCLC) remains clinically challenging, especially during advanced stages of the disease. This study developed an adoptive T-cell treatment through expression of a chimeric antigen receptor (CAR) to target human epidermal growth factor receptor (EGFR)...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, He, Huang, Yao, Jiang, Du-Qing, Cui, Lian-Zhen, He, Zhou, Wang, Chao, Zhang, Zhi-Wei, Zhu, Hai-Li, Ding, Yong-Mei, Li, Lin-Fang, Li, Qiang, Jin, Hua-Jun, Qian, Qi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833445/
https://www.ncbi.nlm.nih.gov/pubmed/29415996
http://dx.doi.org/10.1038/s41419-017-0238-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833445/
https://www.ncbi.nlm.nih.gov/pubmed/29415996
http://dx.doi.org/10.1038/s41419-017-0238-6

Ejemplares similares