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Antitumor activity of EGFR-specific CAR T cells against non-small-cell lung cancer cells in vitro and in mice

Effective control of non-small-cell lung cancer (NSCLC) remains clinically challenging, especially during advanced stages of the disease. This study developed an adoptive T-cell treatment through expression of a chimeric antigen receptor (CAR) to target human epidermal growth factor receptor (EGFR)...

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Detalles Bibliográficos
Autores principales:	Li, He, Huang, Yao, Jiang, Du-Qing, Cui, Lian-Zhen, He, Zhou, Wang, Chao, Zhang, Zhi-Wei, Zhu, Hai-Li, Ding, Yong-Mei, Li, Lin-Fang, Li, Qiang, Jin, Hua-Jun, Qian, Qi-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833445/ https://www.ncbi.nlm.nih.gov/pubmed/29415996 http://dx.doi.org/10.1038/s41419-017-0238-6

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