Cargando…

2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation

Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833449/
https://www.ncbi.nlm.nih.gov/pubmed/29352205
http://dx.doi.org/10.1038/s41419-017-0091-7