Cargando…
2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation
Recent study demonstrated that chronic exposure to solvents increases the risk of Parkinson’s disease (PD), the second most common neurodegenerative disorder characterized by progressive dopaminergic neurodegeneration in the substantia nigra (SN). n-Hexane, a widely used organic solvent, displays ce...
Autores principales: | Zhang, Cong, Hou, Liyan, Yang, Jie, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833449/ https://www.ncbi.nlm.nih.gov/pubmed/29352205 http://dx.doi.org/10.1038/s41419-017-0091-7 |
Ejemplares similares
-
Correction: 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation
por: Zhang, Cong, et al.
Publicado: (2022) -
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway
por: Hou, Liyan, et al.
Publicado: (2017) -
NADPH oxidase-derived H(2)O(2) mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease
por: Hou, Liyan, et al.
Publicado: (2017) -
Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization
por: Che, Yuning, et al.
Publicado: (2018) -
Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase
por: Jiang, Lulu, et al.
Publicado: (2016)