Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver

Elevated homocysteine (Hcy) levels have been reported to be involved in liver injury, and autophagy plays an important role in normal hepatic physiology and pathophysiology, but the mechanism underlying Hcy regulated autophagy is currently unknown. In this study, CBS(+/-) mice were fed with regular...

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Detalles Bibliográficos
Autores principales: Yang, Anning, Jiao, Yun, Yang, Songhao, Deng, Mei, Yang, Xiaoling, Mao, Caiyan, Sun, Yue, Ding, Ning, Li, Nan, Zhang, Minghao, Jin, Shaoju, Zhang, Huiping, Jiang, Yideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833451/
https://www.ncbi.nlm.nih.gov/pubmed/29415998
http://dx.doi.org/10.1038/s41419-017-0216-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833451/
https://www.ncbi.nlm.nih.gov/pubmed/29415998
http://dx.doi.org/10.1038/s41419-017-0216-z

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