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Homocysteine activates autophagy by inhibition of CFTR expression via interaction between DNA methylation and H3K27me3 in mouse liver
Elevated homocysteine (Hcy) levels have been reported to be involved in liver injury, and autophagy plays an important role in normal hepatic physiology and pathophysiology, but the mechanism underlying Hcy regulated autophagy is currently unknown. In this study, CBS(+/-) mice were fed with regular...
Autores principales: | Yang, Anning, Jiao, Yun, Yang, Songhao, Deng, Mei, Yang, Xiaoling, Mao, Caiyan, Sun, Yue, Ding, Ning, Li, Nan, Zhang, Minghao, Jin, Shaoju, Zhang, Huiping, Jiang, Yideng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833451/ https://www.ncbi.nlm.nih.gov/pubmed/29415998 http://dx.doi.org/10.1038/s41419-017-0216-z |
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