Genome-wide DNA methylation analysis reveals that mouse chemical iPSCs have closer epigenetic features to mESCs than OSKM-integrated iPSCs

Induced pluripotent stem cells can be derived from somatic cells through ectopic expression of transcription factors or chemical cocktails. Chemical iPSCs (C-iPSCs) and OSKM-iPSCs (4F-iPSCs) have been suggested to have similar characteristics to mouse embryonic stem cells (mESCs). However, their epi...

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Detalles Bibliográficos
Autores principales: Ping, Wangfang, Hu, Jian, Hu, Gongcheng, Song, Yawei, Xia, Qing, Yao, Mingze, Gong, Shixin, Jiang, Cizhong, Yao, Hongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833453/
https://www.ncbi.nlm.nih.gov/pubmed/29416007
http://dx.doi.org/10.1038/s41419-017-0234-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833453/
https://www.ncbi.nlm.nih.gov/pubmed/29416007
http://dx.doi.org/10.1038/s41419-017-0234-x

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