Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy

Senescence is a tumor suppressive mechanism that induces a permanent proliferative arrest in response to an oncogenic insult or to the genotoxic stress induced by chemotherapy. We have recently described that some cells can escape this arrest, either because senescence was incomplete or as a consequ...

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Detalles Bibliográficos
Autores principales: Le Duff, Mélanie, Gouju, Julien, Jonchère, Barbara, Guillon, Jordan, Toutain, Bertrand, Boissard, Alice, Henry, Cécile, Guette, Catherine, Lelièvre, Eric, Coqueret, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833455/
https://www.ncbi.nlm.nih.gov/pubmed/29415991
http://dx.doi.org/10.1038/s41419-017-0209-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833455/
https://www.ncbi.nlm.nih.gov/pubmed/29415991
http://dx.doi.org/10.1038/s41419-017-0209-y

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