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Regulation of senescence escape by the cdk4–EZH2–AP2M1 pathway in response to chemotherapy
Senescence is a tumor suppressive mechanism that induces a permanent proliferative arrest in response to an oncogenic insult or to the genotoxic stress induced by chemotherapy. We have recently described that some cells can escape this arrest, either because senescence was incomplete or as a consequ...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833455/ https://www.ncbi.nlm.nih.gov/pubmed/29415991 http://dx.doi.org/10.1038/s41419-017-0209-y |