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TCF7L2 positively regulates aerobic glycolysis via the EGLN2/HIF-1α axis and indicates prognosis in pancreatic cancer

Patients with pancreatic ductal adenocarcinoma have much worse prognoses, and much effort has been directed toward understanding the molecular biological aspects of this disease. Accumulated evidence suggests that constitutive activation of the Wnt/β-catenin signalling contributes to the oncogenesis...

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Detalles Bibliográficos
Autores principales: Xiang, Jinfeng, Hu, Qiangsheng, Qin, Yi, Ji, Shunrong, Xu, Wenyan, Liu, Wensheng, Shi, Si, Liang, Chen, Liu, Jiang, Meng, Qingcai, Liang, Dingkong, Ni, Quanxing, Xu, Jin, Zhang, Bo, Yu, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833500/
https://www.ncbi.nlm.nih.gov/pubmed/29476053
http://dx.doi.org/10.1038/s41419-018-0367-6