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Notch1 is a prognostic factor that is distinctly activated in the classical and proneural subtype of glioblastoma and that promotes glioma cell survival via the NF-κB(p65) pathway

Glioblastomas (GBMs) are the most prevalent and devastating primary intracranial malignancies and have extensive heterogeneity. Notch1 signaling is a more complex process in the development of numerous cell and tissue types, including gliomagenesis and progression, and is upregulated in glioma-initi...

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Detalles Bibliográficos
Autores principales: Hai, Long, Zhang, Chen, Li, Tao, Zhou, Xingchen, Liu, Bo, Li, Shuai, Zhu, Meng, Lin, Yu, Yu, Shengping, Zhang, Kai, Ren, Bingcheng, Ming, Haolang, Huang, Yubao, Chen, Lei, Zhao, Pengfei, Zhou, Hua, Jiang, Tao, Yang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833555/
https://www.ncbi.nlm.nih.gov/pubmed/29410396
http://dx.doi.org/10.1038/s41419-017-0119-z