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Honokiol induces apoptosis and autophagy via the ROS/ERK1/2 signaling pathway in human osteosarcoma cells in vitro and in vivo

Osteosarcoma is the most common primary malignant tumor of bone, the long-term survival of which has stagnated in the past several decades. In the present study, we investigated the anticancer effect of honokiol (HNK), an active component isolated and purified from the magnolia officinalis on human...

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Detalles Bibliográficos
Autores principales: Huang, Kangmao, Chen, Yanyan, Zhang, Rui, Wu, Yizheng, Ma, Yan, Fang, Xiangqian, Shen, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833587/
https://www.ncbi.nlm.nih.gov/pubmed/29410403
http://dx.doi.org/10.1038/s41419-017-0166-5