YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

Impaired epithelial regeneration is a crucial pathophysiological feature of ulcerative colitis (UC). Yes-associated protein (YAP1) appears to control cell proliferation and differentiation. In this study, we sought to identify the roles of YAP in intestinal epithelial cell (IEC) self-renewal, regene...

Descripción completa

Detalles Bibliográficos
Autores principales: Deng, Feihong, Peng, Liang, Li, Zhijun, Tan, Gao, Liang, Erbo, Chen, Shengbo, Zhao, Xinmei, Zhi, Fachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833613/
https://www.ncbi.nlm.nih.gov/pubmed/29396428
http://dx.doi.org/10.1038/s41419-017-0244-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833613/
https://www.ncbi.nlm.nih.gov/pubmed/29396428
http://dx.doi.org/10.1038/s41419-017-0244-8

Ejemplares similares