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YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury

Impaired epithelial regeneration is a crucial pathophysiological feature of ulcerative colitis (UC). Yes-associated protein (YAP1) appears to control cell proliferation and differentiation. In this study, we sought to identify the roles of YAP in intestinal epithelial cell (IEC) self-renewal, regene...

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Detalles Bibliográficos
Autores principales:	Deng, Feihong, Peng, Liang, Li, Zhijun, Tan, Gao, Liang, Erbo, Chen, Shengbo, Zhao, Xinmei, Zhi, Fachao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833613/ https://www.ncbi.nlm.nih.gov/pubmed/29396428 http://dx.doi.org/10.1038/s41419-017-0244-8

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