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SPRY2 is a novel MET interactor that regulates metastatic potential and differentiation in rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a predominantly pediatric soft-tissue cancer where the tumor cells exhibit characteristics of the developing skeletal muscle, and the two most common sub-types are embryonal and alveolar RMS. Elevated activation of the receptor tyrosine kinase (RTK) MET is frequent in RMS a...

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Detalles Bibliográficos
Autores principales: Saini, Masum, Verma, Aakanksha, Mathew, Sam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833614/
https://www.ncbi.nlm.nih.gov/pubmed/29445192
http://dx.doi.org/10.1038/s41419-018-0261-2