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Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function
Regulatory T cells in rejected allograft patients display an inability to control responder T cells. Galectin-1 (Gal1) inhibits responder T cells through binding CD7. We investigated whether the dysfunctional immunoregulation in liver allograft rejection patients results from reduced regulatory T-ce...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833641/ https://www.ncbi.nlm.nih.gov/pubmed/29463785 http://dx.doi.org/10.1038/s41419-017-0220-3 |