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Dysfunctional immunoregulation in human liver allograft rejection associated with compromised galectin-1/CD7 pathway function

Regulatory T cells in rejected allograft patients display an inability to control responder T cells. Galectin-1 (Gal1) inhibits responder T cells through binding CD7. We investigated whether the dysfunctional immunoregulation in liver allograft rejection patients results from reduced regulatory T-ce...

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Detalles Bibliográficos
Autores principales: Wei, Sidong, Cao, Ding, Liu, Zuojin, Li, Jinheng, Wu, Hao, Gong, Jianping, Liu, Yiming, Wu, Yakun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833641/
https://www.ncbi.nlm.nih.gov/pubmed/29463785
http://dx.doi.org/10.1038/s41419-017-0220-3