Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart

Our previous studies showed that both exogenous and endogenous FGF21 inhibited cardiac apoptosis at the early stage of type 1 diabetes. Whether FGF21 induces preventive effect on type 2 diabetes-induced cardiomyopathy was investigated in the present study. High-fat-diet/streptozotocin-induced type 2...

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Detalles Bibliográficos
Autores principales: Yang, Hong, Feng, Anyun, Lin, Sundong, Yu, Lechu, Lin, Xiufei, Yan, Xiaoqing, Lu, Xuemian, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833682/
https://www.ncbi.nlm.nih.gov/pubmed/29445083
http://dx.doi.org/10.1038/s41419-018-0307-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833682/
https://www.ncbi.nlm.nih.gov/pubmed/29445083
http://dx.doi.org/10.1038/s41419-018-0307-5

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