Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment

Interleukin 7 receptor (il7r), a transmembrane receptor, belongs to the type I cytokine receptor family. Il7r is involved in the pathogenesis of neurodegenerative disorders, such as multiple sclerosis. Targeted knockdown of il7r leads to delayed myelination, highlighting the potential role of il7r i...

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Detalles Bibliográficos
Autores principales: Cai, Shijiao, Chen, Yang, Shang, Yue, Cui, Jianlin, Li, Zongjin, Li, Yuhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833684/
https://www.ncbi.nlm.nih.gov/pubmed/29449560
http://dx.doi.org/10.1038/s41419-018-0337-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833684/
https://www.ncbi.nlm.nih.gov/pubmed/29449560
http://dx.doi.org/10.1038/s41419-018-0337-z

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