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Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence
Cellular senescence response is (i) activated by numerous stresses, (ii) is characterized by a stable proliferation arrest, and (iii) by a set of specific features. Timely regulated senescence is thought to be beneficial, whereas chronic senescence such as during normal or premature aging is deleter...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833687/ https://www.ncbi.nlm.nih.gov/pubmed/29449545 http://dx.doi.org/10.1038/s41419-018-0300-z |