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Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival

Metabolic reprogramming is pivotal to sustain cancer growth and progression. As such dietary restriction therapy represents a promising approach to starve and treat cancers. Nonetheless, tumors are dynamic and heterogeneous populations of cells with metabolic activities modulated by spatial and temp...

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Detalles Bibliográficos
Autores principales: Wang, Lian, Shang, Zhouchun, Zhou, Yang, Hu, Xinyu, Chen, Yihong, Fan, Yantao, Wei, Xiaoyu, Wu, Liang, Liang, Qiujuan, Zhang, Jun, Gao, Zhengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833690/
https://www.ncbi.nlm.nih.gov/pubmed/29434213
http://dx.doi.org/10.1038/s41419-017-0242-x