Cargando…

LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycle

Although endometrial cancer is the most common type of gynecological malignancy in developed countries, its molecular etiology is not well understood. Leucine-rich repeat and immunoglobulin-like domain 2 (LRIG2) is an evolutionarily conserved gene, but its functions in the endometrium are unknown. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Suh, Dae-Shik, Park, Si Eun, Jin, Hanyong, Lee, Kangseok, Bae, Jeehyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833696/
https://www.ncbi.nlm.nih.gov/pubmed/29358688
http://dx.doi.org/10.1038/s41389-017-0019-1